Lys-SMCC-DM1
Lys-SMCC-DM1 (Lys-Nε-MCC-DM1) is a agent-linker conjugates for ADC that can inhibit tubulin polymerization. Lys-SMCC-DM1 is the active metabolite of T-DM1. T-DM1 is a HER2-targeting ADC with a tubulin polymerization inhibitor DM1. Lys-SMCC-DM1 can be used in the research of breast cancer.
| Trivial name | Lys-Nε-MCC-DM1 |
| Catalog Number | E7895 |
| Molecular Formula | C27H28F3N5O2S |
| CAS# | 1281816-04-3 |
| Inchi | InChI=1S/C27H28F3N5O2S/c1-17(19-5-3-4-6-20(19)27(28,29)30)37-23-14-24(38-25(23)26(31)36)35-16-32-21-8-7-18(13-22(21)35)15-34-11-9-33(2)10-12-34/h3-8,13-14,16-17H,9-12,15H2,1-2H3,(H2,31,36)/t17-/m1/s1 |
| Inchi Key | ZHJGWYRLJUCMRT-QGZVFWFLSA-N |
| SMILES | CC(C1=CC=CC=C1C(F)(F)F)OC2=C(SC(=C2)N3C=NC4=C3C=C(C=C4)CN5CCN(CC5)C)C(=O)N |
| Size | 1mg |
| Supplier Page | http://www.selleckchem.com/products/lys-smcc-dm1.html |
| Additional Information | https://file.selleck.cn/downloads/struct/e7895-lys-smcc-dm1-chemical-structure-tube.png |