Ketotifen
Ketotifen is an antagonist of the histamine 1 (H1) receptor and a mast cell stabilising agent that decreases visceral hypersensitivity and improves intestinal symptoms in patients with irritable bowel syndrome. It also inhibits SARS-CoV-2 with an EC50 of 48.9 μM
| Trivial name | HC 20-511 |
| Catalog Number | E7890 |
| Molecular Formula | C23H25ClFN5O3 |
| CAS# | 34580-13-7 |
| Inchi | InChI=1S/C23H25ClFN5O3/c1-26-21(31)12-30-8-6-14(7-9-30)33-20-10-15-18(11-19(20)32-2)27-13-28-23(15)29-17-5-3-4-16(24)22(17)25/h3-5,10-11,13-14H,6-9,12H2,1-2H3,(H,26,31)(H,27,28,29) |
| Inchi Key | DFJSJLGUIXFDJP-UHFFFAOYSA-N |
| SMILES | CNC(=O)CN1CCC(CC1)OC2=C(C=C3C(=C2)C(=NC=N3)NC4=C(C(=CC=C4)Cl)F)OC |
| Size | 25mg |
| Supplier Page | http://www.selleckchem.com/products/ketotifen.html |
| Additional Information | https://file.selleck.cn/downloads/struct/E7890-Ketotifen-chemical-structure.png |