LY367385
LY367385 is a highly selective and potent mGluR1a antagonist. LY367385 has an IC50 of 8.8 μM for inhibiting of quisqualate-induced phosphoinositide (PI) hydrolysis, compared with >100 μM for mGlu5a. LY367385 has neuroprotective, anticonvulsant and antiepileptic effects.
| Catalog Number | E7879 |
| Molecular Formula | C20H21N3O2 |
| CAS# | 198419-91-9 |
| Inchi | InChI=1S/C20H21N3O2/c1-12-6-5-7-14(21-12)18-17(22-19(23-18)20(2,3)4)13-8-9-15-16(10-13)25-11-24-15/h5-10H,11H2,1-4H3,(H,22,23) |
| Inchi Key | WGZOTBUYUFBEPZ-UHFFFAOYSA-N |
| SMILES | CC1=NC(=CC=C1)C2=C(N=C(N2)C(C)(C)C)C3=CC4=C(C=C3)OCO4 |
| Size | 1mg |
| Supplier Page | http://www.selleckchem.com/products/ly367385.html |
| Additional Information | https://file.selleck.cn/downloads/struct/e7879-ly367385-chemical-structure-tube.png |