ON-013100
ON-013100 is a benzylstyrylsulfone antineoplastic agent and a potent mitotic inhibitor. It inhibits CDK4 and cyclin D1 expression while suppressing MDM2 and reducing p53 levels, disrupting mitogenic signaling and enhancing its anticancer activity.
| Catalog Number | E7822 |
| Molecular Formula | C29H32ClF3N2O3 |
| CAS# | 865783-95-5 |
| Inchi | InChI=1S/C29H31F3N2O3.ClH/c1-33-28(35)27(20-7-5-4-6-8-20)34-16-15-21-17-25(36-2)26(37-3)18-23(21)24(34)14-11-19-9-12-22(13-10-19)29(30,31)32;/h4-10,12-13,17-18,24,27H,11,14-16H2,1-3H3,(H,33,35);1H/t24 -,27+;/m0./s1 |
| Inchi Key | BYGBTDRDPBJUBB-LHIMUUITSA-N |
| SMILES | CNC(=O)C(C1=CC=CC=C1)N2CCC3=CC(=C(C=C3C2CCC4=CC=C(C=C4)C(F)(F)F)OC)OC.Cl |
| Size | 1mg |
| Supplier Page | http://www.selleckchem.com/products/on-013100.html |
| Additional Information | https://file.selleck.cn/downloads/struct/E7822-ON-013100-chemical-structure.png |