TTA-A2
TTA-A2 is a potent and selective antagonist of T-type calcium channel with an IC50 of 9.4 nM, and reduced PXR activation, promoting slow-wave sleep in mice. It shows strong efficacy in rodent models of epilepsy and sleep, making it a valuable preclinical tool for the research of a variety of human neurological diseases.
| Catalog Number | E7819 |
| Molecular Formula | C22H31N3O6S2 |
| CAS# | 953778-63-7 |
| Inchi | InChI=1S/C22H31N3O6S2/c1-11-15-14(12(2)26)18(27)25(15)16(19(28)30-10-31-20(29)22(3,4)5)17(11)33-13-8-24(9-13)21-23-6-7-32-21/h11-15,26H,6-10H2,1-5H3/t11-,12-,14-,15-/m1/s1 |
| Inchi Key | SNUDIPVBUUXCDG-QHSBEEBCSA-N |
| SMILES | CC1C2C(C(=O)N2C(=C1SC3CN(C3)C4=NCCS4)C(=O)OCOC(=O)C(C)(C)C)C(C)O |
| Size | 1mg |
| Supplier Page | http://www.selleckchem.com/products/tta-a2.html |
| Additional Information | https://file.selleck.cn/downloads/struct/e7819-tta-a2-chemical-structure-tube.png |