20(S)-Hydroxycholesterol
20(S)-hydroxyCholesterol (20α-Hydroxycholesterol) is an allosteric activator of the oncoprotein smoothened (Smo) that activates the hedgehog (Hh) signaling pathway with an EC50 of 3 μM in a gene transcription reporter assay using NIH3T3 cells.
| Trivial name | 20α-Hydroxycholesterol |
| Catalog Number | E7817 |
| Molecular Formula | C26H24F4N6O |
| CAS# | 516-72-3 |
| Inchi | InChI=1S/C26H24F4N6O/c1-34(25(37)20-8-7-16(27)15-21(20)26(28,29)30)17-10-13-36(14-11-17)24-19-6-4-3-5-18(19)23(32-33-24)22-9-12-31-35(22)2/h3-9,12,15,17H,10-11,13-14H2,1-2H3 |
| Inchi Key | SZBGQDXLNMELTB-UHFFFAOYSA-N |
| SMILES | CN1C(=CC=N1)C2=NN=C(C3=CC=CC=C32)N4CCC(CC4)N(C)C(=O)C5=C(C=C(C=C5)F)C(F)(F)F |
| Size | 1mg |
| Supplier Page | http://www.selleckchem.com/products/20-s-hydroxycholesterol.html |
| Additional Information | https://file.selleck.cn/downloads/struct/e7817-20-s-hydroxycholesterol-chemical-structure-tube.png |
