ML224
ML224 (NCGC00242364) is a selective TSHR antagonist with an IC50 value of 2.1 µM. ML224 can be used in the study of Graves’ disease and other thyroid disorders.
| Trivial name | NCGC00242364, ANTAG3 |
| Catalog Number | E7781 |
| Molecular Formula | C17H14Cl2F2N2O3 |
| CAS# | 1338824-21-7 |
| Inchi | InChI=1S/C17H14Cl2F2N2O3/c18-11-6-22-7-12(19)15(11)23-16(24)10-3-4-13(26-17(20)21)14(5-10)25-8-9-1-2-9/h3-7,9,17H,1-2,8H2,(H,22,23,24) |
| Inchi Key | MNDBXUUTURYVHR-UHFFFAOYSA-N |
| SMILES | C1CC1COC2=C(C=CC(=C2)C(=O)NC3=C(C=NC=C3Cl)Cl)OC(F)F |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/ml224.html |
| Additional Information | https://file.selleck.cn/downloads/struct/e7781-ml224-chemical-structure-tube.png |