Prinaberel
Prinaberel (ERB-041) is a potent and selective estrogen receptor (ER) β agonist with IC50s of 5.4, 3.1 and 3.7 nM for human, rat and mouse ERβ, respectively. Prinaberel displays >200-fold selectivity for ERβ over ERα. Prinaberel is a potent skin cancer chemopreventive agent that acts by dampening the WNT/β-catenin signaling pathway. Prinaberel induces ovarian cancer apoptosis.
| Trivial name | ERB-041 |
| Catalog Number | E7672 |
| Molecular Formula | C7H15Cl2N2O2P.H2O |
| CAS# | 524684-52-4 |
| Inchi | InChI=1S/C7H15Cl2N2O2P.H2O/c8-2-5-11(6-3-9)14(12)10-4-1-7-13-14;/h1-7H2,(H,10,12);1H2 |
| Inchi Key | PWOQRKCAHTVFLB-UHFFFAOYSA-N |
| SMILES | C1CNP(=O)(OC1)N(CCCl)CCCl.O |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/prinaberel.html |
| Additional Information | https://file.selleck.cn/downloads/struct/e7672-prinaberel-chemical-structure-tube.png |