Delavirdine
Delavirdine (U 90152) is a potent, highly specific and orally active non-nucleoside reverse transcriptase inhibitor (NNRTI). Delavirdine selectively inhibits HIV-1 reverse transcriptase (RT) (IC50=0.26 μM) over DNA polymerase α (IC50=440 μM) and polymerase δ (IC50>550 μM). Delavirdine is an inhibitor of HIV-1 replication and can can be used for the study of AIDs.
| Trivial name | U 90152, BHAP-U 90152 |
| Catalog Number | E7534 |
| Molecular Formula | C26H29NO.C6H8O7 |
| CAS# | 136817-59-9 |
| Inchi | InChI=1S/C26H29NO.C6H8O7/c1-4-25(21-11-7-5-8-12-21)26(22-13-9-6-10-14-22)23-15-17-24(18-16-23)28-20-19-27(2)3;7-3(8)1-6(13,5(11)12)2-4(9)10/h5-18H,4,19-20H2,1-3H3;13H,1-2H2,(H,7,8)(H,9,10)(H,11,12)/b2 6-25-; |
| Inchi Key | FQZYTYWMLGAPFJ-OQKDUQJOSA-N |
| SMILES | CCC(=C(C1=CC=CC=C1)C2=CC=C(C=C2)OCCN(C)C)C3=CC=CC=C3.C(C(=O)O)C(CC(=O)O)(C(=O)O)O |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/delavirdine-e7534.html |
| Additional Information | https://file.selleck.cn/downloads/struct/e7534-delavirdine-chemical-structure-tube.png |