ATN-224
ATN-224 is a second-generation tetrathiomolybdate analogue and an orally active inhibitor of Cu2+/Zn2+-superoxide dismutase 1 (SOD1) with an IC50 of 17.5 nM. It inhibits angiogenesis and tumor growth and can be used in advanced solid and advanced hematologic malignancies research.
| Trivial name | Bis(choline)tetrathiomolybdate |
| Catalog Number | E7527 |
| Molecular Formula | C12H14N2O2 |
| CAS# | 649749-10-0 |
| Inchi | InChI=1S/C12H14N2O2/c1-2-12(9-6-4-3-5-7-9)10(15)13-8-14-11(12)16/h3-7H,2,8H2,1H3,(H,13,15)(H,14,16) |
| Inchi Key | DQMZLTXERSFNPB-UHFFFAOYSA-N |
| SMILES | CCC1(C(=O)NCNC1=O)C2=CC=CC=C2 |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/atn-224.html |
| Additional Information | https://file.selleck.cn/downloads/struct/E7527-ATN-224-chemical-structure.png |