AZ-23
AZ-23 is an ATP-competitive and orally bioavailable Trk kinase A/B/C inhibitor with IC50s of 2 nM (TrkA), 8 nM (TrkB), 24 nM (FGFR1), 52 nM (Flt3), 55 nM (Ret), 84 nM (MuSk), 99 nM (Lck), respectively.
| Trivial name | AZ23, AZ 23 |
| Catalog Number | E7504 |
| Molecular Formula | C11H12N2S.HCl |
| CAS# | 915720-21-7 |
| Inchi | InChI=1S/C11H12N2S.ClH/c1-2-4-9(5-3-1)10-8-13-6-7-14-11(13)12-10;/h1-5,10H,6-8H2;1H/t10-;/m1./s1 |
| Inchi Key | LAZPBGZRMVRFKY-HNCPQSOCSA-N |
| SMILES | C1CSC2=NC(CN21)C3=CC=CC=C3.Cl |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/az-23.html |
| Additional Information | https://file.selleck.cn/downloads/struct/e7504-az-23-chemical-structure-tube.png |