K145 hydrochloride
K145 hydrochloride is a selective, substrate-competitive and orally active SphK2 inhibitor with an IC50 of 4.3 μM and a Ki of 6.4 μM. K145 hydrochloride is inactive against SphK1 and other protein kinases. K145 hydrochloride induces cell apoptosis and has potently antitumor activity.
Catalog Number | E7460 |
Molecular Formula | C20H22O3 |
CAS# | 1449240-68-9 |
Inchi | InChI=1S/C20H22O3/c1-20(2,3)16-9-5-14(6-10-16)18(21)13-19(22)15-7-11-17(23-4)12-8-15/h5-12H,13H2,1-4H3 |
Inchi Key | XNEFYCZVKIDDMS-UHFFFAOYSA-N |
SMILES | CC(C)(C)C1=CC=C(C=C1)C(=O)CC(=O)C2=CC=C(C=C2)OC |
Size | 5mg |
Supplier Page | http://www.selleckchem.com/products/k145-hydrochloride.html |
Additional Information | https://file.selleck.cn/downloads/struct/e7460-k145-hydrochloride-chemical-structure-tube.png |