Veliparib dihydrochloride
Veliparib dihydrochloride is an orally active and potent inhibitor of both PARP-1 and PARP-2 with Kis of 5.2 nM and 2.9 nM, respectively. It exhibit ability to cross the blood-brain barrier and potentiate DNA-damaging agents in preclinical tumor model.
| Trivial name | ABT-888 dihydrochloride |
| Catalog Number | E7366 |
| Molecular Formula | C16H12FN3O3 |
| CAS# | 912445-05-7 |
| Inchi | InChI=1S/C16H12FN3O3/c1-23-16(22)20-15-18-12-7-4-10(8-13(12)19-15)14(21)9-2-5-11(17)6-3-9/h2-8H,1H3,(H2,18,19,20,22) |
| Inchi Key | CPEUVMUXAHMANV-UHFFFAOYSA-N |
| SMILES | COC(=O)NC1=NC2=C(N1)C=C(C=C2)C(=O)C3=CC=C(C=C3)F |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/veliparib-dihydrochloride.html |
| Additional Information | https://file.selleck.cn/downloads/struct/E7366-Veliparib-dihydrochloride-chemical-structure.png |
