Atrasentan
Atrasentan (ABT-627, (+)-A 127722, A-147627) is an antagonist of endothelin A (ETA) receptor with a Ki of 0.034 nM. It exhibits antitumor activity by inhibiting prostate cancer cell growth and inducing apoptotic cell death.
| Trivial name | ABT-627, (+)-A 127722, A-147627 |
| Catalog Number | E7301 |
| Molecular Formula | C32H32O13S |
| CAS# | 173937-91-2 |
| Inchi | InChI=1S/C32H32O13S/c1-37-19-6-13(7-20(38-2)25(19)33)23-14-8-17-18(42-12-41-17)9-15(14)28(16-10-39-30(36)24(16)23)44-32-27(35)26(34)29-21(43-32)11-40-31(45-29)22-4-3-5-46-22/h3-9,16,21,23-24,26-29,31- 35H,10-12H2,1-2H3/t16-,21+,23+,24-,26+,27+,28+,29+,31+,32-/m0/s1 |
| Inchi Key | NRUKOCRGYNPUPR-QBPJDGROSA-N |
| SMILES | COC1=CC(=CC(=C1O)OC)C2C3C(COC3=O)C(C4=CC5=C(C=C24)OCO5)OC6C(C(C7C(O6)COC(O7)C8=CC=CS8)O)O |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/atrasentan.html |
| Additional Information | https://file.selleck.cn/downloads/struct/E7301-Atrasentan-chemical-structure.png |