Ceftriaxone
Ceftriaxone is a long-acting, broad-spectrum β-lactam, third-generation semisynthetic cephalosporin with broad-spectrum antibacterial activity against Gram-positive, Gram-negative, and some anaerobic bacteria. It also acts as a covalent inhibitor of GSK3β with an IC50 of 0.78 μM after 60 minutes of preincubation with the enzyme in vitro.
Trivial name | Ro 13-994 free acid |
Catalog Number | E7201 |
Molecular Formula | C23H27FN4O3 |
CAS# | 73384-59-5 |
Inchi | InChI=1S/C23H27FN4O3/c1-14-17(23(30)28-9-2-3-19(29)22(28)25-14)8-12-27-10-6-15(7-11-27)21-18-5-4-16(24)13-20(18)31-26-21/h4-5,13,15,19,29H,2-3,6-12H2,1H3 |
Inchi Key | PMXMIIMHBWHSKN-UHFFFAOYSA-N |
SMILES | CC1=C(C(=O)N2CCCC(C2=N1)O)CCN3CCC(CC3)C4=NOC5=C4C=CC(=C5)F |
Size | 1mg |
Supplier Page | http://www.selleckchem.com/products/ceftriaxone.html |
Additional Information | https://file.selleck.cn/downloads/struct/E7201-Ceftriaxone-chemical-structure.png |