Indinavir
Indinavir (MK-639 free base) is an orally active and selective HIV-1 protease inhibitor with a Ki of 0.54 nM for PR. Indinavir exhibits anticancer activity by inhibiting the activation of MMPs-2 hydrolysis, anti-angiogenesis and inducing apoptosis. Indinavir is also a SARS-CoV 3CLpro inhibitor.
| Trivial name | MK-639 free base, L-735524 free base |
| Catalog Number | E7034 |
| Molecular Formula | C24H31FO6 |
| CAS# | 150378-17-9 |
| Inchi | InChI=1S/C24H31FO6/c1-20(2)30-19-10-16-15-6-5-13-9-14(27)7-8-21(13,3)23(15,25)17(28)11-22(16,4)24(19,31-20)18(29)12-26/h7-9,15-17,19,26,28H,5-6,10-12H2,1-4H3/t15-,16-,17-,19+,21-,22-,23-,24+/m0/s1 |
| Inchi Key | YNDXUCZADRHECN-JNQJZLCISA-N |
| SMILES | CC1(OC2CC3C4CCC5=CC(=O)C=CC5(C4(C(CC3(C2(O1)C(=O)CO)C)O)F)C)C |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/indinavir.html |
| Additional Information | https://file.selleck.cn/downloads/struct/e7034-indinavir-chemical-structure-tube.png |