Cholesteryl hemisuccinate
Cholesteryl hemisuccinate is a cholesterol derivative and a potent inhibior of DNA polymerase and DNA topoisomerase with an IC50 of 2.9 μM, 6.3 μM, 25 μM for Rat DNA polymerase β, Human DNA polymerase λ and Human DNA topoisomerase I respectively. It exhibits anticancer effect due to its ability to inhibit DNA replication, repair and cell division and can be used in cancer cell growth research.
Catalog Number | E6461 |
Molecular Formula | C14H13N5O5S2 |
CAS# | 1510-21-0 |
Inchi | InChI=1S/C14H13N5O5S2/c1-2-5-3-25-12-8(11(21)19(12)9(5)13(22)23)17-10(20)7(18-24)6-4-26-14(15)16-6/h2,4,8,12,24H,1,3H2,(H2,15,16)(H,17,20)(H,22,23)/b18-7-/t8-,12-/m1/s1 |
Inchi Key | RTXOFQZKPXMALH-GHXIOONMSA-N |
SMILES | C=CC1=C(N2C(C(C2=O)NC(=O)C(=NO)C3=CSC(=N3)N)SC1)C(=O)O |
Size | 1g |
Supplier Page | http://www.selleckchem.com/products/cholesteryl-hemisuccinate.html |
Additional Information | https://file.selleck.cn/downloads/struct/E6461-Cholesteryl-hemisuccinate-chemical-structure.png |