Cholesteryl hemisuccinate
Cholesteryl hemisuccinate is a cholesterol derivative and a potent inhibior of DNA polymerase and DNA topoisomerase with an IC50 of 2.9 μM, 6.3 μM, 25 μM for Rat DNA polymerase β, Human DNA polymerase λ and Human DNA topoisomerase I respectively. It exhibits anticancer effect due to its ability to inhibit DNA replication, repair and cell division and can be used in cancer cell growth research.
Catalog Number | E6461 |
Molecular Formula | C29H30N6O6 |
CAS# | 1510-21-0 |
Inchi | InChI=1S/C29H30N6O6/c1-5-8-23-30-25(29(3,4)38)24(27(36)39-16-22-17(2)40-28(37)41-22)35(23)15-18-11-13-19(14-12-18)20-9-6-7-10-21(20)26-31-33-34-32-26/h6-7,9-14,38H,5,8,15-16H2,1-4H3,(H,31,32,33,34) |
Inchi Key | UQGKUQLKSCSZGY-UHFFFAOYSA-N |
SMILES | CCCC1=NC(=C(N1CC2=CC=C(C=C2)C3=CC=CC=C3C4=NNN=N4)C(=O)OCC5=C(OC(=O)O5)C)C(C)(C)O |
Size | 100mg |
Supplier Page | http://www.selleckchem.com/products/cholesteryl-hemisuccinate.html |
Additional Information | https://file.selleck.cn/downloads/struct/E6461-Cholesteryl-hemisuccinate-chemical-structure.png |