Sulindac sulfide

Sulindac sulfide is a potent, reversible and noncompetitive inhibitor of γ42-secretase with an IC50 of 20.2 μM. It preferentially reduces Aβ42 generation, inhibits Aβ40 and Notch intracellular domain production, and can be used in Alzheimer’s disease research.

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Trivial name	cis-Sulindac sulfide
Catalog Number	E6426
Molecular Formula	C16H24N2O4
CAS#	49627-27-2
Inchi	InChI=1S/C16H24N2O4/c1-10(2)8-13(16(21)22)18-15(20)14(19)12(17)9-11-6-4-3-5-7-11/h3-7,10,12-14,19H,8-9,17H2,1-2H3,(H,18,20)(H,21,22)/t12-,13+,14+/m1/s1
Inchi Key	VGGGPCQERPFHOB-RDBSUJKOSA-N
SMILES	CC(C)CC(C(=O)O)NC(=O)C(C(CC1=CC=CC=C1)N)O
Size	100mg
Supplier Page	http://www.selleckchem.com/products/sulindac-sulfide.html
Additional Information	https://file.selleck.cn/downloads/struct/E6426-Sulindac-sulfide-chemical-structure.png