BMS-986449

BMS-986449 is a CELMoD molecular glue and a degrader of IKZF2/IKZF4. It redirects the E3 ubiquitin ligase Cereblon to induce the degradation of Helios and Eos in Treg cells, to enhance antitumor immunity, and shows promise for advanced solid tumor research.

Price Not Available 25mg BMS-986449 Supplier Page

Catalog Number	E6404
Molecular Formula	C26H21N3O2S
Inchi	InChI=1S/C26H21N3O2S/c1-31-22-8-5-19-15-21(4-3-20(19)16-22)25-24(17-11-13-27-14-12-17)28-26(29-25)18-6-9-23(10-7-18)32(2)30/h3-16H,1-2H3,(H,28,29)
Inchi Key	SINQIEAULQKUPD-UHFFFAOYSA-N
SMILES	COC1=CC2=C(C=C1)C=C(C=C2)C3=C(NC(=N3)C4=CC=C(C=C4)S(=O)C)C5=CC=NC=C5
Size	25mg
Supplier Page	http://www.selleckchem.com/products/bms-986449.html
Additional Information	https://file.selleck.cn/downloads/struct/E6404-BMS-986449-chemical-structure-tube.png