2′-C-Methylcytidine
2′-C-Methylcytidine (NM107) is a potent and selective inhibitor of Chronic hepatitis C virus (HCV) NS5B polymerase with an EC50 of 1.85 μM in wild-type replicon cells. It also effectively inhibits foot-and-mouth disease virus(FMDV) replication with an EC50 of 6.4 μM. Therefore it is a potent antiviral that targets both viral and host factors, making it a promising option for HCV therapy and a potential prophylactic or therapeutic agent against FMDV outbreaks.
Trivial name | NM107 |
Catalog Number | E6045 |
Molecular Formula | C16H17Cl2N5O2 |
CAS# | 20724-73-6 |
Inchi | InChI=1S/C16H17Cl2N5O2/c17-10-2-1-3-11(18)13(10)15(24)22-12-8-20-23-14(12)16(25)21-9-4-6-19-7-5-9/h1-3,8-9,19H,4-7H2,(H,20,23)(H,21,25)(H,22,24) |
Inchi Key | OVPNQJVDAFNBDN-UHFFFAOYSA-N |
SMILES | C1CNCCC1NC(=O)C2=C(C=NN2)NC(=O)C3=C(C=CC=C3Cl)Cl |
Size | 100mg |
Supplier Page | http://www.selleckchem.com/products/2-c-methylcytidine.html |
Additional Information | https://file.selleck.cn/downloads/struct/E6045-2-C-Methylcytidine-chemical-structure.png |