2′-C-Methylcytidine
2′-C-Methylcytidine (NM107) is a potent and selective inhibitor of Chronic hepatitis C virus (HCV) NS5B polymerase with an EC50 of 1.85 μM in wild-type replicon cells. It also effectively inhibits foot-and-mouth disease virus(FMDV) replication with an EC50 of 6.4 μM. Therefore it is a potent antiviral that targets both viral and host factors, making it a promising option for HCV therapy and a potential prophylactic or therapeutic agent against FMDV outbreaks.
Trivial name | NM107 |
Catalog Number | E6045 |
Molecular Formula | C31H29N5O6S |
CAS# | 20724-73-6 |
Inchi | InChI=1S/C31H29N5O6S/c1-19-9-10-20(15-28(19)42-4)31(37)33-21-11-13-25(14-12-21)43(38,39)36-30-29(34-26-7-5-6-8-27(26)35-30)32-22-16-23(40-2)18-24(17-22)41-3/h5-18H,1-4H3,(H,32,34)(H,33,37)(H,35,36) |
Inchi Key | HJSSPYJVWLTYHG-UHFFFAOYSA-N |
SMILES | CC1=C(C=C(C=C1)C(=O)NC2=CC=C(C=C2)S(=O)(=O)NC3=NC4=CC=CC=C4N=C3NC5=CC(=CC(=C5)OC)OC)OC |
Size | 25mg |
Supplier Page | http://www.selleckchem.com/products/2-c-methylcytidine.html |
Additional Information | https://file.selleck.cn/downloads/struct/E6045-2-C-Methylcytidine-chemical-structure.png |