Cilastatin sodium
Cilastatin sodium (MK0791 sodium) is a reversible, competitive inhibitor of renal dehydropeptidase I (also known as membrane dipeptidase, MDP), with an IC50 of 0.1 µM. It is primarily used in combination with imipenem to enhance the antibiotic’s effectiveness against a broad spectrum of bacterial infections by preventing its degradation in the kidneys.
| Trivial name | MK0791 sodium |
| Catalog Number | E6033 |
| Molecular Formula | C20H34O5 |
| CAS# | 81129-83-1 |
| Inchi | InChI=1S/C20H34O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h12-13,15-17,19,21,23H,2-11,14H2,1H3,(H,24,25)/b13-12+/t15-,16+,17+,19+/m0/s1 |
| Inchi Key | GMVPRGQOIOIIMI-DWKJAMRDSA-N |
| SMILES | CCCCCC(C=CC1C(CC(=O)C1CCCCCCC(=O)O)O)O |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/cilastatin-sodium.html |
| Additional Information | https://file.selleck.cn/downloads/struct/E6033-Cilastatin-sodium-chemical-structure.png |