Selumetinib sulfate

Selumetinib sulfate (AZD6244 sulfate, ARRY-142886 sulfate) is an oral, non-ATP-competitive inhibitor of MEK1/2, with an IC50 of 14 nmol/L against purified MEK1. It exhibits an anti-tumor effect in the HT-29 xenograft model and is used to treat cancer and inflammation.

Price Not Available 50mg Selumetinib sulfate Supplier Page

Trivial name	AZD6244 sulfate, ARRY-142886 sulfate
Catalog Number	E6024
Molecular Formula	C21H23Cl2N5O2S
CAS#	943332-08-9
Inchi	InChI=1S/C21H23Cl2N5O2S/c1-2-25-19(29)17-10-13-18(26-21(24)27-20(13)31-17)12-9-16(15(23)11-14(12)22)30-8-7-28-5-3-4-6-28/h9-11H,2-8H2,1H3,(H,25,29)(H2,24,26,27)
Inchi Key	WJUNQSYQHHIVFX-UHFFFAOYSA-N
SMILES	CCNC(=O)C1=CC2=C(N=C(N=C2S1)N)C3=CC(=C(C=C3Cl)Cl)OCCN4CCCC4
Size	50mg
Supplier Page	http://www.selleckchem.com/products/selumetinib-sulfate.html
Additional Information	https://file.selleck.cn/downloads/struct/E6024-Selumetinib-sulfate-chemical-structure.png