CP-100356 hydrochloride

CP-100356 hydrochloride is an orally active dual inhibitor of MDR1 (P-gp) and BCRP, with IC50 of ∼0.5 µM for MDR1-mediated calcein-AM transport inhibition and ∼1.5 µM for BCRP-mediated prazosin transport inhibition. It is also a weak inhibitor of OATP1B1 (IC50 ∼ 66 µM).

Price Not Available 1g CP-100356 hydrochloride Supplier Page

Catalog Number	E5985
Molecular Formula	C14H8N2O
CAS#	142715-48-8
Inchi	InChI=1S/C14H8N2O/c17-14-9-5-2-1-4-8(9)13-12-10(14)6-3-7-11(12)15-16-13/h1-7H,(H,15,16)
Inchi Key	ACPOUJIDANTYHO-UHFFFAOYSA-N
SMILES	C1=CC=C2C(=C1)C3=NNC4=CC=CC(=C43)C2=O
Size	1g
Supplier Page	http://www.selleckchem.com/products/cp-100356-hydrochloride.html
Additional Information	https://file.selleck.cn/downloads/struct/E5985-CP-100356-hydrochloride-chemical-structure.png