CP-100356 hydrochloride

CP-100356 hydrochloride is an orally active dual inhibitor of MDR1 (P-gp) and BCRP, with IC50 of ∼0.5 µM for MDR1-mediated calcein-AM transport inhibition and ∼1.5 µM for BCRP-mediated prazosin transport inhibition. It is also a weak inhibitor of OATP1B1 (IC50 ∼ 66 µM).

Price Not Available 100mg CP-100356 hydrochloride Supplier Page

Catalog Number	E5985
Molecular Formula	C15H13N5OS
CAS#	142715-48-8
Inchi	InChI=1S/C15H13N5OS/c21-14(17-8-11-4-2-1-3-5-11)12-9-22-15(19-12)20-13-6-7-16-10-18-13/h1-7,9-10H,8H2,(H,17,21)(H,16,18,19,20)
Inchi Key	DOBKQCZBPPCLEG-UHFFFAOYSA-N
SMILES	C1=CC=C(C=C1)CNC(=O)C2=CSC(=N2)NC3=NC=NC=C3
Size	100mg
Supplier Page	http://www.selleckchem.com/products/cp-100356-hydrochloride.html
Additional Information	https://file.selleck.cn/downloads/struct/E5985-CP-100356-hydrochloride-chemical-structure.png