Ebio1
Ebio1 is a subtype-selective activator of the voltage-gated potassium channel KCNQ2 that enhances conductance through a unique twist-to-open mechanism. It induces conformational changes in the S6 helix, increasing channel activity at a saturating voltage (+50 mV).
| Catalog Number | E5975 |
| Molecular Formula | C15H13N5OS |
| CAS# | 339287-36-4 |
| Inchi | InChI=1S/C15H13N5OS/c21-14(17-8-11-4-2-1-3-5-11)12-9-22-15(19-12)20-13-6-7-16-10-18-13/h1-7,9-10H,8H2,(H,17,21)(H,16,18,19,20) |
| Inchi Key | DOBKQCZBPPCLEG-UHFFFAOYSA-N |
| SMILES | C1=CC=C(C=C1)CNC(=O)C2=CSC(=N2)NC3=NC=NC=C3 |
| Size | 1g |
| Supplier Page | http://www.selleckchem.com/products/ebio1.html |
| Additional Information | https://file.selleck.cn/downloads/struct/E5975-Ebio1-chemical-structure.png |