Ebio1
Ebio1 is a subtype-selective activator of the voltage-gated potassium channel KCNQ2 that enhances conductance through a unique twist-to-open mechanism. It induces conformational changes in the S6 helix, increasing channel activity at a saturating voltage (+50 mV).
| Catalog Number | E5975 |
| Molecular Formula | C19H9Cl2F2N3OS |
| CAS# | 339287-36-4 |
| Inchi | InChI=1S/C19H9Cl2F2N3OS/c20-11-2-1-3-12(21)17(11)18-14-5-7-16(25-26(14)9-24-19(18)27)28-15-6-4-10(22)8-13(15)23/h1-9H |
| Inchi Key | VEPKQEUBKLEPRA-UHFFFAOYSA-N |
| SMILES | C1=CC(=C(C(=C1)Cl)C2=C3C=CC(=NN3C=NC2=O)SC4=C(C=C(C=C4)F)F)Cl |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/ebio1.html |
| Additional Information | https://file.selleck.cn/downloads/struct/E5975-Ebio1-chemical-structure.png |