DDD85646
DDD85646 (IMP-366) is an orally active inhibitor of N-myristoyltransferase(NMT), with an IC50 of 2 nM for Trypanosoma brucei NMT (TbNMT) and 4 nM for human NMT (hNMT). It exhibits a potential for treating human African trypanosomiasis.
| Trivial name | IMP-366 |
| Catalog Number | E5974 |
| Molecular Formula | C20H25NO4 |
| CAS# | 1215010-55-1 |
| Inchi | InChI=1S/C20H25NO4/c1-24-17-7-6-15(12-18(17)25-16-4-2-3-5-16)20(13-21)10-8-14(9-11-20)19(22)23/h6-7,12,14,16H,2-5,8-11H2,1H3,(H,22,23) |
| Inchi Key | CFBUZOUXXHZCFB-UHFFFAOYSA-N |
| SMILES | COC1=C(C=C(C=C1)C2(CCC(CC2)C(=O)O)C#N)OC3CCCC3 |
| Size | 25mg |
| Supplier Page | http://www.selleckchem.com/products/ddd85646.html |
| Additional Information | https://file.selleck.cn/downloads/struct/E5974-DDD85646-chemical-structure.png |