PRDX1-IN-1
PRDX1-IN-1 is a celastrol-ligustrazine hybrid and a potent inhibitor of peroxiredoxin 1 (PRDX1) with an IC50 of 0.164 μM. It induces ROS accumulation, inhibits cancer cell growth and metastasis, and exhibits strong antitumor efficacy, making it a promising candidate for lung cancer therapy.
| Catalog Number | E5960 |
| Molecular Formula | C8H8N2O3S |
| CAS# | 2996096-63-8 |
| Inchi | InChI=1S/C8H8N2O3S/c9-14(11,12)5-7-6-3-1-2-4-8(6)13-10-7/h1-4H,5H2,(H2,9,11,12) |
| Inchi Key | UBQNRHZMVUUOMG-UHFFFAOYSA-N |
| SMILES | C1=CC=C2C(=C1)C(=NO2)CS(=O)(=O)N |
| Size | 25mg |
| Supplier Page | http://www.selleckchem.com/products/prdx1-in-1.html |
| Additional Information | https://file.selleck.cn/downloads/struct/E5960-PRDX1-IN-1-chemical-structure.png |