Enpatoran
Enpatoran is a potent, selective inhibitor of Toll-like receptors 7 and 8 (TLR7/8), with IC50 of 11.1 nM and 24.1 nM, respectively, in HEK293 cells. It also demonstrates potential for treating autoimmune diseases.
Trivial name | M5049 |
Catalog Number | E5922 |
Molecular Formula | C12H7N3O2S |
CAS# | 2101938-42-3 |
Inchi | InChI=1S/C12H7N3O2S/c16-11-10(18-12(17)15-11)6-7-1-2-8-9(5-7)14-4-3-13-8/h1-6H,(H,15,16,17)/b10-6- |
Inchi Key | SQWZFLMPDUSYGV-POHAHGRESA-N |
SMILES | C1=CC2=NC=CN=C2C=C1C=C3C(=O)NC(=O)S3 |
Size | 25mg |
Supplier Page | http://www.selleckchem.com/products/enpatoran.html |
Additional Information | https://file.selleck.cn/downloads/struct/E5922-Enpatoran-chemical-structure.png |