Enpatoran
Enpatoran is a potent, selective inhibitor of Toll-like receptors 7 and 8 (TLR7/8), with IC50 of 11.1 nM and 24.1 nM, respectively, in HEK293 cells. It also demonstrates potential for treating autoimmune diseases.
| Trivial name | M5049 |
| Catalog Number | E5922 |
| Molecular Formula | C19H27N5O4.HCl |
| CAS# | 2101938-42-3 |
| Inchi | InChI=1S/C19H27N5O4.ClH/c1-24(8-5-7-21-18(25)14-6-4-9-28-14)19-22-13-11-16(27-3)15(26-2)10-12(13)17(20)23-19;/h10-11,14H,4-9H2,1-3H3,(H,21,25)(H2,20,22,23);1H |
| Inchi Key | YTNKWDJILNVLGX-UHFFFAOYSA-N |
| SMILES | CN(CCCNC(=O)C1CCCO1)C2=NC3=CC(=C(C=C3C(=N2)N)OC)OC.Cl |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/enpatoran.html |
| Additional Information | https://file.selleck.cn/downloads/struct/E5922-Enpatoran-chemical-structure.png |