RS47
RS47 is a potent and specific inhibitor of the non-canonical NF-κB signaling pathway through disrupting RelB binding to its target DNA with a Kd values of 1.1 μM. It is shown to inhibit colorectal cancer (CRC) cells and B lymphoma growth, holds potential as a research tool for targeting cancers driven by hyperactive non-canonical NF-κB signaling.
| Catalog Number | E5916 |
| Molecular Formula | C16H20FN3O4 |
| CAS# | 301655-16-3 |
| Inchi | InChI=1S/C16H20FN3O4/c1-11(21)18-9-13-10-20(16(22)24-13)12-2-3-15(14(17)8-12)19-4-6-23-7-5-19/h2-3,8,13H,4-7,9-10H2,1H3,(H,18,21)/t13-/m0/s1 |
| Inchi Key | TYZROVQLWOKYKF-ZDUSSCGKSA-N |
| SMILES | CC(=O)NCC1CN(C(=O)O1)C2=CC(=C(C=C2)N3CCOCC3)F |
| Size | 1g |
| Supplier Page | http://www.selleckchem.com/products/rs47.html |
| Additional Information | https://file.selleck.cn/downloads/struct/E5916-RS47-chemical-structure.png |