Asandeutertinib
Asandeutertinib (Osimertinib-d3, AZD-9291-d3) is an orally administered, ATP-competitive, irreversible, deuterated third-generation Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor (EGFR TKI) and a deuterium-stabilized derivative of osimertinib, with the potential to treat advanced EGFR-mutated NSCLC.
| Trivial name | Osimertinib-d3, AZD-9291-d3 |
| Catalog Number | E5912 |
| Molecular Formula | C29H39N5O8 |
| CAS# | 1638281-46-5 |
| Inchi | InChI=1S/C29H39N5O8/c1-28(2,3)31-11-17(35)32-15-10-16(33(4)5)13-8-12-9-14-21(34(6)7)24(38)20(27(30)41)26(40)29(14,42)25(39)18(12)23(37)19(13)22(15)36/h10,12,14,21,31,36,38-39,42H,8-9,11H2,1-7H3,(H2,30 ,41)(H,32,35)/t12-,14-,21-,29-/m0/s1 |
| Inchi Key | FPZLLRFZJZRHSY-HJYUBDRYSA-N |
| SMILES | CC(C)(C)NCC(=O)NC1=CC(=C2CC3CC4C(C(=O)C(=C(C4(C(=O)C3=C(C2=C1O)O)O)O)C(=O)N)N(C)C)N(C)C |
| Size | 25mg |
| Supplier Page | http://www.selleckchem.com/products/asandeutertinib.html |
| Additional Information | https://file.selleck.cn/downloads/struct/e5912-Asandeutertinib-chemical-structure.png |