GNF362
GNF362 is a highly selective and potent orally available inhibitor of inositol trisphosphate 3’ kinase B (Itpkb) with an IC50 of 9 nM, it also inhibits Itpka and Itpkc with IC50 values of 20 nM and 19 nM, respectively. It can be used in research to study treatment for T cell-mediated autoimmune diseases.
Catalog Number | E5908 |
Molecular Formula | C10H12N2O4 |
CAS# | 1003019-41-7 |
Inchi | InChI=1S/C10H12N2O4/c1-6-4-12(10(15)11-9(6)14)8-3-2-7(5-13)16-8/h2-4,7-8,13H,5H2,1H3,(H,11,14,15)/t7-,8+/m0/s1 |
Inchi Key | XNKLLVCARDGLGL-JGVFFNPUSA-N |
SMILES | CC1=CN(C(=O)NC1=O)C2C=CC(O2)CO |
Size | 1g |
Supplier Page | http://www.selleckchem.com/products/gnf362.html |
Additional Information | https://file.selleck.cn/downloads/struct/E5908-GNF362-chemical-structure.png |