AM-9022
AM-9022 is an orally active, potent, and selective inhibitor of KIF18A, a mitotic kinesin motor protein critical for chromosome alignment and segregation. It exhibits significant anti-cancer effects in human breast and ovarian tumor models.
| Catalog Number | E5883 |
| Molecular Formula | C17H18N6 |
| CAS# | 2446872-46-2 |
| Inchi | InChI=1S/C17H18N6/c18-7-5-15(12-3-1-2-4-12)23-10-13(9-22-23)16-14-6-8-19-17(14)21-11-20-16/h6,8-12,15H,1-5H2,(H,19,20,21)/t15-/m1/s1 |
| Inchi Key | HFNKQEVNSGCOJV-OAHLLOKOSA-N |
| SMILES | C1CCC(C1)C(CC#N)N2C=C(C=N2)C3=C4C=CNC4=NC=N3 |
| Size | 1g |
| Supplier Page | http://www.selleckchem.com/products/am-9022.html |
| Additional Information | https://file.selleck.cn/downloads/struct/E5883-AM-9022-chemical-structure.png |