LY294002 hydrochloride
LY294002 hydrochloride is a potent and specific inhibitor of PI3K with an IC50 of 0.5 μM, 0.97 μM, and 0.57 μM for P110α, P110β, P110δ, respectively. It also acts as a direct blocker of L-type Ca2+ channel with IC50 of 20 µM.
Catalog Number | E5875 |
Molecular Formula | C30H31F3N8O |
CAS# | 934389-88-5 |
Inchi | InChI=1S/C30H31F3N8O/c1-19-4-7-23(13-27(19)39-29-36-10-8-26(38-29)22-14-34-18-35-15-22)37-28(42)20-5-6-21(25(12-20)30(31,32)33)16-41-11-9-24(17-41)40(2)3/h4-8,10,12-15,18,24H,9,11,16-17H2,1-3H3,(H,37, 42)(H,36,38,39)/t24-/m0/s1 |
Inchi Key | ZGBAJMQHJDFTQJ-DEOSSOPVSA-N |
SMILES | CC1=C(C=C(C=C1)NC(=O)C2=CC(=C(C=C2)CN3CCC(C3)N(C)C)C(F)(F)F)NC4=NC=CC(=N4)C5=CN=CN=C5 |
Size | 1g |
Supplier Page | http://www.selleckchem.com/products/ly294002-hydrochloride.html |
Additional Information | https://file.selleck.cn/downloads/struct/E5875-LY294002-hydrochloride-chemical-structure.png |