MASM7
MASM7 is an activator of mitofusins that promotes mitochondrial fusion through mitofusins. It increases mitochondrial AR in MEFs in a concentration-dependent manner, with an EC50 value of 75 nM. MASM7 also directly binds to the HR2 domain of MFN2 with a dissociation constant (Kd) of 1.1 μM, effectively activating MFN2 or MFN to induce fusion.
| Catalog Number | E5826 |
| Molecular Formula | C5H10N2O7P2 |
| CAS# | 920868-45-7 |
| Inchi | InChI=1S/C5H10N2O7P2/c8-5(15(9,10)11,16(12,13)14)3-7-2-1-6-4-7/h1-2,4,8H,3H2,(H2,9,10,11)(H2,12,13,14) |
| Inchi Key | XRASPMIURGNCCH-UHFFFAOYSA-N |
| SMILES | C1=CN(C=N1)CC(O)(P(=O)(O)O)P(=O)(O)O |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/masm7.html |
| Additional Information | https://file.selleck.cn/downloads/struct/E5826-MASM7-chemical-structure.png |