Lenumlostat
Lenumlostat (PAT-1251, GB2064) is a potent, selective, and orally available inhibitor of lysyl oxidase-like 2 (LOXL2). It exhibits greater selectivity for LOXL2 over other family members, with IC50 of 0.71 μM for hLOXL2 and 1.17 μM for hLOXL3. It also possesses anti-fibrotic properties.
| Trivial name | PAT-1251; GB2064 |
| Catalog Number | E5824 |
| Molecular Formula | C3H9NNa2O7P2 |
| CAS# | 2007885-39-2 |
| Inchi | InChI=1S/C3H11NO7P2.2Na/c4-2-1-3(5,12(6,7)8)13(9,10)11;;/h5H,1-2,4H2,(H2,6,7,8)(H2,9,10,11);;/q;2*+1/p-2 |
| Inchi Key | CEYUIFJWVHOCPP-UHFFFAOYSA-L |
| SMILES | C(CN)C(O)(P(=O)(O)[O-])P(=O)(O)[O-].[Na+].[Na+] |
| Size | 25mg |
| Supplier Page | http://www.selleckchem.com/products/lenumlostat.html |
| Additional Information | https://file.selleck.cn/downloads/struct/E5824-Lenumlostat-chemical-structure.png |