Fedratinib hydrochloride hydrate

Fedratinib hydrochloride hydrate (TG-101348 hydrochloride hydrate, SAR 302503 hydrochloride hydrate) is a small-molecule, ATP-competitive inhibitor of JAK2 with IC50s of 3 nM for both JAK2 and JAK2V617F kinase. It induces cancer cell apoptosis and has potential for efficacious treatment of JAK2V617F-associated myeloproliferative disease.

Price Not Available 5mg Fedratinib hydrochloride hydrate Supplier Page

Trivial name	TG-101348 hydrochloride hydrate, SAR 302503 hydrochloride hydrate
Catalog Number	E5818
Molecular Formula	C20H27N5O2
CAS#	1374744-69-0
Inchi	InChI=1S/C20H27N5O2/c26-20-12-9-15-14-17(10-11-18(15)21-20)27-13-5-4-8-19-22-23-24-25(19)16-6-2-1-3-7-16/h10-11,14,16H,1-9,12-13H2,(H,21,26)
Inchi Key	RRGUKTPIGVIEKM-UHFFFAOYSA-N
SMILES	C1CCC(CC1)N2C(=NN=N2)CCCCOC3=CC4=C(C=C3)NC(=O)CC4
Size	5mg
Supplier Page	http://www.selleckchem.com/products/fedratinib-hydrochloride-hydrate.html
Additional Information	https://file.selleck.cn/downloads/struct/E5818-Fedratinib-hydrochloride-hydrate-chemical-structure.png