PF-07265028
PF-07265028 is a potent and selective inhibitor of hematopoietic progenitor kinase 1 (HPK1/MAP4K1) with a Ki of <0.05 nM, and exhibits potent cellular activity, with a pSLP76 IC50 of 17 nM.
| Catalog Number | E5816 |
| Molecular Formula | C27H28N2O7 |
| CAS# | 2736458-30-1 |
| Inchi | InChI=1S/C27H28N2O7/c1-18-23(26(30)35-14-8-11-20-9-5-4-6-10-20)25(21-12-7-13-22(17-21)29(32)33)24(19(2)28-18)27(31)36-16-15-34-3/h4-13,17,25,28H,14-16H2,1-3H3/b11-8+ |
| Inchi Key | KJEBULYHNRNJTE-DHZHZOJOSA-N |
| SMILES | CC1=C(C(C(=C(N1)C)C(=O)OCC=CC2=CC=CC=C2)C3=CC(=CC=C3)[N+](=O)[O-])C(=O)OCCOC |
| Size | 1mg |
| Supplier Page | http://www.selleckchem.com/products/pf-07265028.html |
| Additional Information | https://file.selleck.cn/downloads/struct/E5816-PF-07265028-chemical-structure.png |