JNJ-28583113

JNJ-28583113 is a potent, brain-penetrant antagonist of TRPM2 with an IC50 of 126 nM that protects cells from oxidative stress-induced death and morphological changes. It also inhibits microglial cytokine release in response to pro-inflammatory stimuli and promotes GSK3α/β phosphorylation.

Price Not Available 5mg JNJ-28583113 Supplier Page

Catalog Number	E5813
Molecular Formula	C11H16FN3O3
CAS#	2765255-93-2
Inchi	InChI=1S/C11H16FN3O3/c1-2-3-4-5-6-13-10(17)15-7-8(12)9(16)14-11(15)18/h7H,2-6H2,1H3,(H,13,17)(H,14,16,18)
Inchi Key	AOCCBINRVIKJHY-UHFFFAOYSA-N
SMILES	CCCCCCNC(=O)N1C=C(C(=O)NC1=O)F
Size	5mg
Supplier Page	http://www.selleckchem.com/products/jnj-28583113.html
Additional Information	https://file.selleck.cn/downloads/struct/E5813-JNJ-28583113-chemical-structure.png