Gliocidin
Gliocidin (SW106065), is a nicotinamide-mimetic prodrug that targets glioblastoma cells with an IC50 of 150 nM, by exploiting a de novo purine synthesis vulnerability via indirect inhibition of IMPDH2. It readily crosses the BBB and can be used in the treatment of all malignant brain tumors.
| Trivial name | SW106065 |
| Catalog Number | E5804 |
| Molecular Formula | C9H18N6 |
| CAS# | 62289-81-0 |
| Inchi | InChI=1S/C9H18N6/c1-13(2)7-10-8(14(3)4)12-9(11-7)15(5)6/h1-6H3 |
| Inchi Key | UUVWYPNAQBNQJQ-UHFFFAOYSA-N |
| SMILES | CN(C)C1=NC(=NC(=N1)N(C)C)N(C)C |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/gliocidin.html |
| Additional Information | https://file.selleck.cn/downloads/struct/E5804-Gliocidin-chemical-structure.png |