Oxidopamine hydrochloride
Oxidopamine (6-OHDA) hydrochloride is an antagonist of the neurotransmitter dopamine. Oxidopamine hydrochloride is a widely used neurotoxin and selectively destroys dopaminergic neurons. Oxidopamine hydrochloride promotes COX-2 activation, leading to PGE2 synthesis and pro-inflammatory cytokine IL-1β secretion. Oxidopamine hydrochloride can be used for the research of Parkinson’s disease (PD), attention-deficit hyperactivity disorder (ADHD), and Lesch-Nyhan syndrome.
Trivial name | 6-Hydroxydopamine Hydrochloride |
Catalog Number | E5793 |
Molecular Formula | C23H18ClF2N3O3S |
CAS# | 28094-15-7 |
Inchi | InChI=1S/C23H18ClF2N3O3S/c1-2-9-33(31,32)29-19-8-7-18(25)20(21(19)26)22(30)17-12-28-23-16(17)10-14(11-27-23)13-3-5-15(24)6-4-13/h3-8,10-12,29H,2,9H2,1H3,(H,27,28) |
Inchi Key | GPXBXXGIAQBQNI-UHFFFAOYSA-N |
SMILES | CCCS(=O)(=O)NC1=C(C(=C(C=C1)F)C(=O)C2=CNC3=C2C=C(C=N3)C4=CC=C(C=C4)Cl)F |
Size | 5mg |
Supplier Page | http://www.selleckchem.com/products/oxidopamine-hydrochloride.html |
Additional Information | https://file.selleck.cn/downloads/struct/e5793-oxidopamine-hydrochloride-chemical-structure-tube.png |