SB 202190 hydrochloride
SB 202190 hydrochloride is a selective inhibitor of p38 MAP kinase with IC50 values of 50 nM for p38α and 100 nM for p38β2. It exhibits anti-cancer activity, induces autophagy, and is studied for its role in hippocampus-dependent spatial memory and apoptotic regulation under chronic ischemia.
Catalog Number | E5786 |
Molecular Formula | C28H41N7O3 |
CAS# | 350228-36-3 |
Inchi | InChI=1S/C28H41N7O3/c1-8-35(9-2)13-11-10-12-29-26-30-18-20-16-23(19-14-21(37-6)17-22(15-19)38-7)25(31-24(20)32-26)33-27(36)34-28(3,4)5/h14-18H,8-13H2,1-7H3,(H3,29,30,31,32,33,34,36) |
Inchi Key | DXCUKNQANPLTEJ-UHFFFAOYSA-N |
SMILES | CCN(CC)CCCCNC1=NC2=NC(=C(C=C2C=N1)C3=CC(=CC(=C3)OC)OC)NC(=O)NC(C)(C)C |
Size | 5mg |
Supplier Page | http://www.selleckchem.com/products/sb-202190-hydrochloride.html |
Additional Information | https://file.selleck.cn/downloads/struct/E5786-SB-202190-hydrochloride-chemical-structure.png |