5-Fluorouridine
5-Fluorouridine is a uridine analog and a potent inhibitor of ribozyme self-cleavage with an EC50 of 5.9 μM. It significantly inhibit ribozyme function via its covalent incorporation into the mRNA carrying the ribozyme sequences and can be used as used chemotherapeutic agent in cancer research.
Catalog Number | E5785 |
Molecular Formula | C22H18Cl2N8 |
CAS# | 316-46-1 |
Inchi | InChI=1S/C22H18Cl2N8/c1-13-10-29-21(31-13)17-12-30-22(32-20(17)16-4-3-15(23)8-18(16)24)27-7-6-26-19-5-2-14(9-25)11-28-19/h2-5,8,10-12H,6-7H2,1H3,(H,26,28)(H,29,31)(H,27,30,32) |
Inchi Key | AQGNHMOJWBZFQQ-UHFFFAOYSA-N |
SMILES | CC1=CN=C(N1)C2=CN=C(N=C2C3=C(C=C(C=C3)Cl)Cl)NCCNC4=NC=C(C=C4)C#N |
Size | 50mg |
Supplier Page | http://www.selleckchem.com/products/5-fluorouridine.html |
Additional Information | https://file.selleck.cn/downloads/struct/E5785-5-Fluorouridine-chemical-structure.png |