Cl-amidine hydrochloride

Cl-amidine hydrochloride is an orally active peptidylarginine deminase (PAD) inhibitor, with IC50 values of 0.8 μM, 6.2 μM and 5.9 μM for PAD1, PAD3, and PAD4, respectively. Cl-amidine hydrochloride induces apoptosis in cancer cells. Cl-amidine hydrochloride induces microRNA (miR)-16 (miRNA-16, microRNA-16) expression and causes cell cycle arrest. Cl-Amidine hydrochloride prevents histone 3 citrullination and neutrophil extracellular trap formation, and improves survival in a murine sepsis model[1][2][3][4][5].

Price Not Available 100mg Cl-amidine hydrochloride Supplier Page

Catalog Number	E4995
Molecular Formula	C21H20ClNO5
CAS#	1373232-26-8
Inchi	InChI=1S/C21H20ClNO5/c1-23-7-6-12(17(27)10-23)19-14(24)8-15(25)20-16(26)9-18(28-21(19)20)11-4-2-3-5-13(11)22/h2-5,8-9,12,17,24-25,27H,6-7,10H2,1H3/t12-,17+/m0/s1
Inchi Key	BIIVYFLTOXDAOV-YVEFUNNKSA-N
SMILES	CN1CCC(C(C1)O)C2=C(C=C(C3=C2OC(=CC3=O)C4=CC=CC=C4Cl)O)O
Size	100mg
Supplier Page	http://www.selleckchem.com/products/cl-amidine-hydrochloride.html
Additional Information	https://file.selleck.cn/downloads/struct/E4995-Cl-amidine-hydrochloride-chemical-structure.png