Fluvastatin
Fluvastatin is a competitive inhibitor of HMG-CoA reductase with an IC50 value of 40 and 100 nM in human liver microsomes. Fluvastatin also exerts cytoprotective effects against oxidative stress through the Nrf2-dependent antioxidant pathway.
| Trivial name | XU 62-320 free acid |
| Catalog Number | E4981 |
| Molecular Formula | C22H16F3N3O2S |
| CAS# | 93957-54-1 |
| Inchi | InChI=1S/C22H16F3N3O2S/c23-22(24,25)30-16-7-5-15(6-8-16)28-21(29)20-19(10-12-31-20)27-13-14-9-11-26-18-4-2-1-3-17(14)18/h1-12,27H,13H2,(H,28,29) |
| Inchi Key | FGTCROZDHDSNIO-UHFFFAOYSA-N |
| SMILES | C1=CC=C2C(=C1)C(=CC=N2)CNC3=C(SC=C3)C(=O)NC4=CC=C(C=C4)OC(F)(F)F |
| Size | 50mg |
| Supplier Page | http://www.selleckchem.com/products/fluvastatin.html |
| Additional Information | https://file.selleck.cn/downloads/struct/E4981-Fluvastatin-chemical-structure.png |