Mozavaptan (hydrochloride)
Mozavaptan hydrochloride(OPC 31260 HCl), a benzazepine derivative is a potent, selective, competitive, and orally active antagonist of vasopressin V2 receptor with an IC50 value of 14 nM. Mozavaptan hydrochloride shows ~85-fold selectivity for V2 receptor over V1 receptor. Mozavaptan hydrochloride has the potential for hyponatremia, syndrome of inappropriate antidiuretic hormone (SIADH), and congestive heart failure treatment.
Trivial name | OPC 31260 HCl |
Catalog Number | E4957 |
Molecular Formula | C16H14BrN5O4S.HCl |
CAS# | 138470-70-9 |
Inchi | InChI=1S/C16H14BrN5O4S.ClH/c1-11-3-5-13(22(23)24)7-15(11)27(25,26)20(2)19-9-14-8-18-16-6-4-12(17)10-21(14)16;/h3-10H,1-2H3;1H/b19-9+; |
Inchi Key | VOUDEIAYNKZQKM-MYHMWQFYSA-N |
SMILES | CC1=C(C=C(C=C1)[N+](=O)[O-])S(=O)(=O)N(C)N=CC2=CN=C3N2C=C(C=C3)Br.Cl |
Size | 1g |
Supplier Page | http://www.selleckchem.com/products/mozavaptan-hydrochloride.html |
Additional Information | https://file.selleck.cn/downloads/struct/E4957-Mozavaptan-hydrochloride-chemical-structure.png |