Bestatin hydrochloride

Bestatin hydrochloride is an inhibitor of aminopeptidase N and enkephalinase that elevates the levels of angiotensin II and angiotensin III. It also acts as a non-competitive inhibitor (α > 1) of porcine DPP-IV with a Ki value of 75 μM. It reduces DPP-IV activity, decreases cell viability, and increases DNA fragmentation in vitro. It has the potential to treat skin conditions like acne, psoriasis and keloids.

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Catalog Number	E4916
Molecular Formula	C21H19ClN4O4
CAS#	65391-42-6
Inchi	InChI=1S/C21H19ClN4O4/c1-29-19-10-17-13(9-14(19)20(23)27)18(6-7-24-17)30-12-4-5-16(15(22)8-12)26-21(28)25-11-2-3-11/h4-11H,2-3H2,1H3,(H2,23,27)(H2,25,26,28)
Inchi Key	WOSKHXYHFSIKNG-UHFFFAOYSA-N
SMILES	COC1=CC2=NC=CC(=C2C=C1C(=O)N)OC3=CC(=C(C=C3)NC(=O)NC4CC4)Cl
Size	5mg
Supplier Page	http://www.selleckchem.com/products/bestatin-hydrochloride.html
Additional Information	https://file.selleck.cn/downloads/struct/E4916-Bestatin-hydrochloride-chemical-structure.png